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L-Glutamic acid-15N,d5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
L-Glutamic acid-15N,d5图片

L-谷氨酸 15N,d5
L-Glutamic acid-15N,d5 是带有 15N 标记和氘代标记的 L-Glutamic acid。L-Glutamic acid 作为一种兴奋性氨基酸神经递质,为谷氨酸盐受体所有亚型(代谢型红藻氨酸、NMDA 和 AMPA)的激动剂。对DA从多巴胺能神经末梢释放的过程有激动作用。
生物活性

L-Glutamic acid-15N,d5 is the deuterium and 15N-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release ofDAfrom dopaminergic terminals.

IC50& Target

AMPA Receptor

 

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

153.15

Formula

C5H4D515NO4

中文名称

L-谷氨酸 15N,d5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

 
 
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