Antibacterial agent 116

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CAS NO:

99330-28-6

Antibacterial agent 116 是一种含二苯甲酮的水杨酰苯胺类化合物。Antibacterial agent 116 能抑制肽聚糖的形成而具有较强的抗菌活性。Antibacterial agent 116 可作为光亲和探针标记Acinetobacter baumannii的青霉素结合蛋白 (PBP1b)，干扰肽聚糖链的生长，阻断其增殖。

生物活性	Antibacterial agent 116 is a benzophenone-containing salicylanilide compound. Antibacterial agent 116 has potent antibacterial activity by inhibiting the peptidoglycan formation. Antibacterial agent 116 is used as a photoaffinity probe to labelAcinetobacter baumanniipenicillin-binding protein(PBP1b), block the propagation pathway to disrupt the growth of peptidoglycan chain^[1].
体外研究 (In Vitro)	Antibacterial agent 116 (compound 1) can photo-labelA. baumanniiPBP1b, targets to R367 and E372 binding site^[1].
分子量	730.12
Formula	C₂₆H₁₅Cl₂I₂NO₄
CAS 号	99330-28-6
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.