CAY10595

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CAY10595

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

916047-16-0

CAY10595 是有效的前列腺素 D2 受体(CRTH2/DP2)的拮抗剂，其对人类的K_i值为 10 nM。

生物活性

CAY10595 is a potentCRTH2/DP2receptor antagonist that binds to the human receptor with aK_iof 10 nM.

IC₅₀& Target^[1]

10 nM (Ki)

体外研究
(In Vitro)

CAY10595 (compound 71) is a potent CRTH2/DP2 receptor antagonist that binds to the human receptor with a K_iof 10 nM^[1].

体内研究
(In Vivo)

Administration of the DP2 antagonist CAY10595 slightly delays the development of CIA. Treatment with CAY10595 reduces IgG2a anti-CII levels without modification of IgG anti-CII levels^[2].

分子量

451.23

Formula

C₂₀H₁₃Cl₂FN₂O₅

CAS 号

916047-16-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.