| 生物活性 | Difopein (TFA), a specific and competitive inhibitor of14-3-3 protein(a highly conserved eukaryotic regulatory molecule), blocking the ability of 14-3-3 to bind to target proteins and inhibits 14-3-3/Ligand interactions. Difopein (TFA) leads to induction ofapoptosisand enhances the ability of cisplatin to kill cells[1]. | ||||||
| IC50& Target | 14-3-3 protein[1] | ||||||
| 分子量 | 6501.19 | ||||||
| 性状 | Solid | ||||||
| Formula | C275H425N76F3O91S6 | ||||||
| Sequence Shortening | SADGAPHCVPRDLSWLDLEANMCLPGAAGLDSADGAPHCVPRDLSWLDLEANMCLPGAAGLE | ||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||
| 储存方式 | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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