Irsenontrine maleate

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1630083-70-3

E2027 maleate

Irsenontrine (E2027) maleate 是一种具有口服活性和选择性的磷酸二酯酶 9 (PDE9) 抑制剂。Irsenontrine maleate 可用于神经系统疾病的研究。

生物活性

Irsenontrine (E2027) maleate is an orally active and selectivephosphodiesterase9 (PDE9) inhibitor. Irsenontrine maleate can be used for the research of neurological diseases^[1]^[2].

IC₅₀& Target

PDE9^[1]

体内研究
(In Vivo)

Irsenontrine (0.3, 3.3 mg/kg; p.o.) maleate exhibits a significant ameliorative effect on the percentage of exploration of the novel object at 3.3 mg/kg in Scopolamine-induced rats^[1].
Irsenontrine (1 mg/kg; p.o.) maleate and memantine hydrochloride (1 mg/kg; p.o.) combined treatment group exhibits a significantly higher percentage of exploration of the novel object than memantine hydrochloride (1 mg/kg) alone^[1].

Clinical Trial

分子量

506.51

Formula

C₂₆H₂₆N₄O₇

CAS 号

1630083-70-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.