sFTX-3,3

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sFTX-3,3

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

141997-14-0

sFTX-3.3 是一种Ca²⁺通道拮抗剂，对 P 型和 N 型 Ca²⁺通道的IC₅₀分别约为 0.24 mM 和 0.70 mM。

生物活性

sFTX-3.3 is aCa²⁺channelantagonist withIC₅₀s of approximately 0.24 mM and 0.70 mM against P-type and N-type channels^[1]^[2].

IC₅₀& Target

P/Q-type calcium channel

0.24 mM (IC₅₀)

N-type calcium channel

0.70 mM (IC₅₀)

体外研究
(In Vitro)

sFTX-3.3 (100 μM) reduces the duration of the slow component of presynaptic calcium currents by about 50% of the control and also reduces presynaptic sodium current by approximately 20% of the control. sFTX-3.3 (100 μM) reduces whole-cell sodium current recorded from SK.N.SH cells by approximately 15%^[3].

分子量

287.40

Formula

C₁₂H₂₉N₇O

CAS 号

141997-14-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.