Rilapladib 是 Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) 的选择性抑制剂 (IC50 = 230 pM) 和血小板活化因子受体的拮抗剂。
产品描述
Rilapladib is a selective inhibitor of Lipoprotein-Associated Phospholipase A2(Lp-PLA2, IC50 = 230 pM) and an antagonist of the platelet activating factor receptor.
体外活性
Rilapladib reduces the PAF biological activity and levels, thereby reducing Lp-PLA2 biosynthesis and preventing the possible adverse effects of Lp-PLA2 [2].
Cas No.
412950-08-4
分子式
C40H38F5N3O3S
分子量
735.81
别名
SB 659032
储存和溶解度
DMSO:78mg/mL (106mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
