RORγt Inverse agonist 8 is a highly potent, specific, orally bioavailable RORγt inverse agonist, with an IC50 of 19 nM for human RORγt-LBD. References: [1]. Guendisch U, et al. Pharmacological inhibition of RORγt suppresses the Th17 pathway and alleviates arthritis in vivo. PLoS One. 2017 Nov 20;12(11):e0188391.

纯度：≥98%

CAS：2079892-79-6