CARM1-IN-1 是 CARM1 的选择性抑制剂，IC50 为 8.6 μM。 CARM1-IN-1 对 PRMT1 和 SET7 的活性较弱，IC50 >600 μM。
产品描述
CARM1-IN-1 is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 >600 μM.
体外活性
In human LNCaP cells, CARM1-IN-1 significantly reduces the PSA promoter activity in a dose-dependent manner[1].
Cas No.
1020399-49-8
分子式
C26H21Br2NO3
分子量
555.26
别名
CARM1-IN-7G
储存和溶解度
DMSO:30 mg/mL (54 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
