3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione 是一种有效的STAT3抑制剂，降低STAT3与DNA结合的能力，对肝癌细胞也有良好的生长抑制作用。

3-methyl-6- (naphthalen-1-yl)pyrimidine-2,4(1H, 3H)-dione is a potent STAT3 inhibitor that reduces the ability of STAT3 to bind to DNA and also has a good growth inhibition effect on liver cancer cells [1].

MNK8 (50 μM, 0-48 h) increased Sub-G1 cells in a time-dependent fashion, and decreases the expression of antiapoptotic proteins such as Bcl-2, survivin, and cyclin D1 [1].

2055078-49-2

C15H12N2O2

252.27

3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years