PF 184 是一种有效的抑制因子-κB 激酶 2 (IKK-2) 抑制剂，IC50 为 37 nM。
| Cas No. | 1187460-81-6 |
| 化学名 | 8-(2-((3S,4S)-3,4-bis(hydroxymethyl)-3,4-dimethylpyrrolidin-1-yl)-5-chloroisonicotinamido)-1-(4-fluorophenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide |
| Canonical SMILES | ClC1=CN=C(C=C1C(NC2=CC=C3C(C(N(C(C=C4)=CC=C4F)N=C5C(N)=O)=C5CC3)=C2)=O)N6C[C@](CO)(C)[C@@](CO)(C)C6 |
| 分子式 | C32H32ClFN6O4 |
| 分子量 | 619.09 |
| 溶解度 | <61.91mg/ml in DMSO |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
