Sinapinic acid 是从Hydnophytum formicarumJACK. 根中分离到的酚类,是HDAC抑制剂,对ACE-I的活性也有抑制作用。它有抗肿瘤活性,诱导肿瘤细胞凋亡,具有抗氧化、抗糖尿病的作用。
产品描述
Sinapic acid protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinapic acid with antioxidant role protects cardiac cells and its functions from I/R induced oxidative stress. Sinapic acid is a potentially useful agent for the protection against liver fibrosis and cirrhosis. Sinapic acid prevents the alterations in the levels of lipids and lipoproteins by virtue of its anti-lipidaemic effect in isoproterenol induced myocardial infarcted rats. Sinapic acid ameliorates hyperglycemia through PLC-PKC signals to enhance the glucose utilization in diabetic rats.
Cas No.
530-59-6
分子式
C11H12O5
分子量
224.212
别名
Sinapic acid;Synapoic acid;芥子酸
储存和溶解度
DMSO:40 mg/mL(178.4 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years