Schisandrin B 是从五味子中分离联苯环辛二烯衍生物,对啮齿类动物的肝脏和心脏的抗氧化作用。
产品描述
Schisandrin B has an antioxidant effect on rodent liver and heart.
体内活性
Schisandrin B can protect liver against toxicant challenge. Schisandrin B pretreatment protects against carbon tetrachloride- or TNFα-induced liver damage in mice. [5] [6] [7] Further studies demonstrate the protective effect of schisandrin B on free radical-induced damage in various vital organs, including the heart, liver, kidney, brain and skin. [8] Moreover, schisandrin B is found to attenuate cancer invasion and metastasis via inhibiting epithelial mesenchymal transition at the step of local invasion. [9]
Cas No.
61281-37-6
分子式
C23H28O6
分子量
400.46
别名
Schisandrin B (Sch B);五味子乙素;Schizandrin B;五味子素B;gamma-Schisandrin;Wuweizisu-B
储存和溶解度
DMSO:74 mg/mL (184.8 mM)
H2O:<1 mgml
Ethanol:10 mg/mL (24.97 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years