YYA021具有高抗HIV活性和低细胞毒性，是一种抑制HIV进入的小分子CD4模拟物,。

YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity.

YYA-021 enhances the neutralization sensitivity of simian-human immunodeficiency virus (SHIV) carrying the envelope from the clade B clinical human immunodeficiency virus type 1 (HIV-1) isolate MNA. [1]

In rats and rhesus macaques, YYA-021 (i.v.) shows moderate half-lives, wide tissue distribution and relatively high distribution volumes. [2]

144217-65-2

C18H27N3O2

317.433

YYA 021

DMSO:50 mg/mL (157.52 mM),Need ultrasonic
H2O:< 0.1 mg/mL (insoluble)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years