H-151 是选择性和共价的STING拮抗剂,可减少 TBK1 磷酸化并抑制 STING 棕榈酰化,在体内外均具有显著的抑制活性,可用于自身炎症性疾病的研究。
产品描述
H-151 is a highly potent, selective and covalent antagonist of STING, reduces TBK1 phosphorylation and suppresses human STING palmitoylation.
Cas No.
941987-60-6
分子式
C17H17N3O
分子量
279.34
储存和溶解度
DMSO:125 mg/mL (447.48 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years