Liriodendrin 调节肺部炎症、NF-kB (p65) 的磷酸化和血管内皮生长因子 (VEGF) 的表达。Liriodendrin具有抗炎、镇痛、降血糖活性,在脓毒症引起的急性肺损伤中起保护作用。
产品描述
Liriodendrin regulates lung inflammation, the phosphorylation of the NF-kB (p65) and expression of vascular endothelial growth factor (VEGF). Liriodendrin has anti-inflammatory, antinociceptive, hypoglycemic activities and plays protective role in sepsis-
体外活性
When Liriodendrin was incubated for 24 h with human intestinal bacteria, two metabolites, (+)-syringaresinol-beta-D-glucopyranoside and (+)-syringaresinol, were produced. The metabolic time course of Liriodendrin was as follows: at early time, Liriodendrin was converted to (+)-syringaresinol-beta-D-glucopyranoside, and then (+)-syringaresinol[1].
Cas No.
573-44-4
分子式
C34H46O18
分子量
742.72
别名
鹅掌楸苦素
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years