20(S)-Hydroxycholesterol是平滑 (Smo) 癌蛋白的变构激活剂。
产品描述
20(S)-Hydroxycholesterol is an allosteric activator of the oncoprotein smoothened (Smo).
体外活性
20(S)-Hydroxycholesterol activates the hedgehog signaling pathway with an EC50 of 3 μM in NIH3T3 cells[2].
Cas No.
516-72-3
分子式
C27H46O2
分子量
402.65
别名
20α-Hydroxycholesterol
储存和溶解度
DMSO:27mg/mL (67.1mM),ultrasonic and warming and heat to 60°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
