Compound W 是 γ-secretase 抑制剂。它导致 Aβ42 和 notch-1 Aβ-like peptide 25 (Nβ25) 的释放水平降低。它是母体血清中 3,3’-diiodothyronine sulfate (T2S) 的交叉反应物质，可作为胎儿甲状腺功能减退的标志物。
产品描述
The compound is an inhibitor of γ-secretase. It also causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25).
Cas No.
173550-33-9
分子式
C19H12N2O8
分子量
396.31
别名
Compound W;3,5-二(4-硝基苯氧基)苯甲酸
储存和溶解度
DMSO:<39.63mg/mL
1.1eq. NaOH:<19.81mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
