WHI-P258 是喹唑啉化合物，结合到JAK3的活性位点(Ki:72 μM)。甚至当WHI-P258到达 100 μM 时也不会抑制 JAK3 ，且对凝血酶诱导的血小板聚集无影响。
产品描述
WHI-P258 is a dimethoxyquinazoline inhibitor of JAK3. This compound binds JAK3 weakly and may be used as a JAK-binding negative control in the development of new therapeutics.
Cas No.
21561-09-1
分子式
C16H15N3O2
分子量
281.31
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
