Duloxetine hydrochloride 是一种 5-羟色胺-去甲肾上腺素重吸收 (serotonin-Norepinephrine reuptake) 抑制剂 (SNRI),Ki=4.6 nM,可用于广泛性焦虑症的研究。
产品描述
Duloxetine hydrochloride is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC and is also used for the treatment of pain in patients with DIABETES MELLITUS and FIBROMYALGIA.
Cas No.
136434-34-9
分子式
C18H20ClNOS
分子量
333.88
别名
Duloxetine HCl;LY-248686 HCl;(S)-Duloxetine hydrochloride;LY-248686 hydrochloride;盐酸度洛西汀
储存和溶解度
Ethanol:<1 mgml
DMSO:67 mg/mL (200.67 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years