HS 024 是一种选择性的MC4受体拮抗剂，可增加食物摄入，对 MC4、MC5、MC3 和 MC1 的Ki分别为 0.29、3.29、5.45 和 18.6 nM。
产品描述
Highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks α-MSH- and MTII-induced hypotension and bradycardia in rats, following central administration in vivo.
Cas No.
212370-59-7
分子式
C58H79N19O10S2
分子量
1266.51
别名
HS 024
储存和溶解度
H2O:0.50 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
