Xylometazoline hydrochloride 是一种 α- 肾上腺素受体激动剂，是一种鼻血管收缩药。
产品描述
Xylometazoline Hydrochloride is an α-adrenoceptor agonist usually used as nasal decongestant.
体外活性
Xylometazoline is an α-adrenoceptor agonist commonly used as nasal decongestant, exhibits highest potency at α2B-adrenoceptor subtype with EC50 of 99 μM. Xylometazoline binds at adrenoceptor subtypeα1A, α1B, α1D, α2A, α2B, α2C with IC50 of 0.08, 0.56, 0.45, 0.98, 1.8, 0.22 μM, repectively. [1]
Cas No.
1218-35-5
分子式
C16H25ClN2
分子量
280.84
别名
盐酸赛洛唑啉;Xylometazoline HCl
储存和溶解度
H2O:51 mg/mL (181.6 mM)
Ethanol:52 mg/mL (185.2 mM)
DMSO:26 mg/mL (92.6 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
