An intermediate in the synthesis of (-)-sitagliptin
| Cas No. | 486460-23-5 |
| 别名 | 西他列汀N-BOC杂质 |
| Canonical SMILES | FC(F)(C1=NN=C2N1CCN(C(C[C@H](NC(OC(C)(C)C)=O)CC3=C(C=C(C(F)=C3)F)F)=O)C2)F |
| 分子式 | C21H23F6N5O3 |
| 分子量 | 507.4 |
| 溶解度 | DMF: 20 mg/mL,DMSO: 16 mg/mL,Ethanol: Slightly soluble,PBS (pH 7.2): 0.25 mg/mL |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | N-Boc sitagliptin is an intermediate in the synthesis of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin .1 1.Anjibabu, R., Boggu, J.M.R., Shekhar, P., et al.Stereoselective synthesis of dipeptidyl peptidase-4 (DPP-4) inhibitor, (R)-sitagliptinChemistrySelect1(17)5445-5447(2016) |
