位置:首页 > 产品库 > MC-Val-Cit-PAB-NH-C2-NH-Boc
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
MC-Val-Cit-PAB-NH-C2-NH-Boc
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MC-Val-Cit-PAB-NH-C2-NH-Boc图片
CAS NO:1616727-22-0
包装与价格:
包装价格(元)
5mg询价
10mg询价
25mg询价

MC-Val-Cit-PAB-NH-C2-NH-Boc 是一种可被组织蛋白酶 (cathepsin) 降解的 ADC 连接子 (ADC linker),可用于合成抗体偶联药物 (ADC)。
Cas No.1616727-22-0
分子式C36H54N8O10
分子量758.86
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

MC-Val-Cit-PAB-NH-C2-NH-Boc is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Akaiwa M, et al. Synthesis and Evaluation of Linear and Macrocyclic Dolastatin 10 Analogues Containing Pyrrolidine Ring Modifications. ACS Omega. 2018;3(5):5212-5221.

 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024