首页 蛋白库 基因库 产品 会员服务
位置：首页 > 产品库 > Ac-IETD-AFC(trifluoroacetate salt)
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
Ac-IETD-AFC(trifluoroacetate salt)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Ac-IETD-AFC(trifluoroacetate salt)图片
包装与价格：
包装价格(元)
1mg询价
5mg询价
10mg询价

A fluorogenic substrate for caspase-8
Canonical SMILESOC(C[C@H](NC(C(NC([C@@H](NC([C@H]([C@@H](C)CC)NC(C)=O)=O)CCC(O)=O)=O)[C@@H](C)O)=O)C(NC(C=C1O2)=CC=C1C(C(F)(F)F)=CC2=O)=O)=O.OC(C(F)(F)F)=O
分子式C31H38F3N5O12• XCF3COOH
分子量729.7
溶解度DMSO: 10 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Ac-IETD-AFC is a fluorogenic substrate that can be cleaved by caspase-8 and related enzymes that recognize the amino acid sequence IETD, including caspase-3 processing enzyme, caspase-10, and granzyme B.1Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.

1.Reszka, P., Schulz, R., Methling, K., et al.Synthesis, enzymatic evaluation, and docking studies of fluorogenic caspase 8 tetrapeptide substratesChemMedChem5(1)103-117(2010)

 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024