Mal-PEG4-VC-PAB-DMEA-PNU-159682

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:	2259318-52-8
包装:	5mg
市场价:	11520元

Mal-PEG4-VC-PAB-DMEA-PNU-159682，一种用于 ADC 的药物-偶联物，由 ADC 接头 Mal-PEG4-VC-PAB 和有效的 ADC 细胞毒素DMEA-PNU-159682 组成。 DMEA-PNU-159682 包括来自肝微粒体代谢产物的新霉素 (MMDX) 和 ADC 细胞毒素 PNU-159682。

Cas No.	2259318-52-8
分子式	C₇₄H₉₈N₁₀O₂₇
分子量	1559.62
储存条件	Store at -20°C, protect from light, stored under nitrogen
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Mal-PEG4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for ADC, consists the ADC linker Mal-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682[1]. [1]. John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1