DBCO-C3-Acid 是一种点击化学 (Click Chemistry) 中间体。DBCO-C3-Acid 可用以合成 ADC linker。
Cas No. | 1207355-31-4 |
分子式 | C20H17NO3 |
分子量 | 319.35 |
溶解度 | DMSO : 100 mg/mL (313.14 mM; Need ultrasonic) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | DBCO-C3-Acid is a Click Chemistry intermediate used in the synthesis of antibody-drug conjugate (ADC) linker[1]. [1]. van Geel R, et al. Chemoenzymatic Conjugation of Toxic Payloads to the Globally Conserved N-Glycan of Native mAbs Provides Homogeneous and Highly Efficacious Antibody-Drug Conjugates. Bioconjug Chem. 2015;26(11):2233-2242. |