6-?Demethoxytangeretin 是一种从柑橘分离的黄酮。它能够促进 CRE 介导的转录 (与海马神经元的学习和记忆相关)。它具有抗炎和抗过敏作用，通过间变性淋巴瘤激酶和丝裂原活化蛋白激酶途径抑制人肥大细胞中 IL-6 的产生和基因表达。
产品描述
6-Demethoxytangeretin is a citrus flavonoid isolated from Citrus depressa.
体外活性
6-Demethoxytangeretin exerts anti-inflammatory activity and anti-allergic activity, suppresses production and gene expression of interleukin-6 in human mast cell-1 via ALK and MAPK pathways [1]. 6-Demethoxytangeretin facilitates the Cre-mediated transcription associated with learning and memory in cultured hippocampal neurons [2].
Cas No.
6601-66-7
分子式
C19H18O6
分子量
342.347
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
