MMAE-SMCC 是由有效的有丝分裂和微管蛋白抑制剂 MMAE 和接头 SMCC 组成的抗体偶联药物，可制成抗体药物偶联物。
| Cas No. | 2021179-11-1 |
| 分子式 | C58H89N7O14S |
| 分子量 | 1140.43 |
| 溶解度 | DMSO : 220 mg/mL (192.91 mM; Need ultrasonic) |
| 储存条件 | Store at -20°C,unstable in solution, ready to use. |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | MMAE-SMCC is a drug-linker conjugate for ADC. MMAE-SMCC is composed of a potent mitotic and a tubulin inhibitor MMAE and a linker SMCC to make antibody drug conjugate[1]. [1]. Tang F, et al. One-pot N-glycosylation remodeling of IgG with non-natural sialylglycopeptides enables glycosite-specific and dual-payload antibody-drug conjugates. Org Biomol Chem. 2016 Oct 12;14(40):9501-9518. |
