MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH 是一种可降解 (cleavable) 的 ADC linker,用于合成可用于合成抗体偶联药物 (ADC)。
Cas No. | 1599440-25-1 |
别名 | 链接子 |
分子式 | C28H36N6O10 |
分子量 | 616.62 |
溶解度 | DMSO : 120 mg/mL (194.61 mM; Need ultrasonic) |
储存条件 | 4°C, away from moisture |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. [1]. Masuda, Takeshi, et al. ConjuguÉ anticorps-mÉdicament. WO2014057687A1. |