CRBN modulator-1，一种 Thalidomide 类似物和 CRBN 调节剂，结合 CRBN 的IC50 值和 Ki 值分别为 3.5 μM 和 0.98 μM。
| Cas No. | 2407829-65-4 |
| 分子式 | C17H12N2O5 |
| 分子量 | 324.29 |
| 溶解度 | DMSO : 10 mg/mL (30.84 mM; ultrasonic and adjust pH to 2 with HCl) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | CRBN modulator-1, a Thalidomide analog and a CRBN modulator extracted from WO2020006262A1, compound 10, has an IC50 of 3.5 μM and a Ki of 0.98 μM[1]. [1]. Nathanael Gray, et al. New crbn modulators. WO2020006262A1. |
