Dorzagliatin 是双重作用的葡萄糖激酶 (Glucokinase;GK) 激活剂，可改善 2 型糖尿病的血糖控制，提高胰腺 β 细胞功能。
产品描述
Dorzagliatin is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.
体内活性
In diabetic rats, Dorzagliatin (low-dose 10?mg/kg, and high-dose 30?mg/kg; administered intragastrically; daily 8:00 AM for one month) shows a glucose-lowering effect on the glucose levels[2].
Cas No.
1191995-00-2
分子式
C22H27ClN4O5
分子量
462.93
别名
HMS5552
储存和溶解度
DMSO:125 mg/mL (270.02 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
