AR453588 HCl is a highly potent and orally bioavailable anti-diabetic glucokinase activator, with an EC50 of 42 nM. AR453588 HCl shows anti-hyperglycemic activity. References: [1]. Hinklin RJ, et al. Discovery and preclinical development of AR453588 as an anti-diabetic glucokinase activator. Bioorg Med Chem. 2020 Jan 1;28(1):115232.

纯度：≥98%

CAS：1065606-97-4