IDO-IN-1 是吲哚胺-2,3-双加氧酶抑制剂,IC50=59 nM。
产品描述
IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays, respectively.)
体外活性
IDO-IN-1 is inactive against tryptophan 2,3-dioxygenase (TOD; IC50 >10 μM).
Cas No.
914638-30-5
分子式
C9H7BrFN5O2
分子量
316.08
别名
4-氨基-N-(3-溴-4-氟苯基)-N'-羟基-1,2,5-恶二唑-3-甲脒
储存和溶解度
DMSO:682 mg/mL (2157.61 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years