Pomalidomide 4'-PEG1-acid 是一种合成的 E3 连接酶配体-接头偶联物,它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 cereblon 配体和 1 单位 PEG 接头。
Cas No. | 2139348-60-8 |
Canonical SMILES | OC(CCOCCNC1=C2C(N(C(C2=CC=C1)=O)C3CCC(NC3=O)=O)=O)=O |
分子式 | C18H19N3O7 |
分子量 | 389.36 |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG1 linker with terminal acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license. |