Loureirin B 是从剑叶龙血树中分离到的一种黄酮，是PAI-1抑制剂，IC50值为 26.10?μM。它抑制KATP，以及ERK和JNK的磷酸化，具有抗糖尿病的功效。
产品描述
Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathway is likely involved.
Cas No.
119425-90-0
分子式
C18H20O5
分子量
316.353
别名
龙血素B;龙血素 B
储存和溶解度
DMSO:150 mg/mL (474.16 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
