Vitamin K具有凝血作用,对凝血因子、基质-Gla蛋白和骨钙素很重要。
产品描述
Vitamin K has blood coagulation action and is important for coagulation factors, matrix-Gla protein, and osteocalcin.
体外活性
Vitamin K plays an important role in nervous system. Vitamin K facilitates the bioactivation of protein Gas6 and protein S, ligands of the TAM family (Tyro3, Axl and Mer) receptor tyrosine kinases. In the brain, vitamin K is involved in the synthesis of sphingolipids [3].
体内活性
Vitamin K supplementation is beneficial in improving insulin sensitivity and glucose tolerance, reducing the risk of type 2 diabetes, and preventing insulin resistance. The recommended intake of adequate vitamin K is 90 micrograms per day for women and 120 micrograms per day for men [2]. Vitamin K deficiency leads to an increase in hypocarboxylated osteocalcin, a decrease in bone mineral density, and an increased probability of fracture. Vitamin K supplementation reduces undercarboxylated osteocalcin and improves bone turnover curves [4].
Cas No.
12001-79-5
别名
Vitamin K1(20);维生素K;Kephton
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years