6-Phosphogluconic acid 是竞争性的磷酸葡萄糖异构酶抑制剂,对6-磷酸果糖和6-磷酸葡萄糖和的Ki分别为 42 μM 和 48 μM。它属于人内源性代谢物。
产品描述
6-Phosphogluconic acid is a potent and competitive inhibitor of phosphoglucose isomerase (PGI).The activity of phosphoglucose isomerase was inhibited intensely and competitively by 6-Phosphogluconic acid, with an apparent Ki of 0.048 mM for glucose 6-phosphate and 0.042 mM for fructose 6-phosphate as the substrate.
体外活性
6-Phosphogluconic acid (0.5-2.0 mM) completely inhibits the activity of PGI with glucose 6-phosphate (0.05- 0.5 mM) as the substrate [1].
Cas No.
921-62-0
分子式
C6H13O10P
分子量
276.14
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years