Acetohexamide是磺脲类试剂，可刺激胰腺分泌胰岛素，能够用于 2 型糖尿病的相关研究。
产品描述
Acetohexamide is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (KIR6.2) with Ki values of 22.9 and 14.2 μM in HEK293 cells transfected with the human receptor and in rat brain, respectively. Acetohexamide is metabolized in the liver to its active metabolite hydroxyhexamide.
Cas No.
968-81-0
分子式
C15H20N2O4S
分子量
324.4
别名
Dymelor;醋磺己脲;Gamadiabet;醋磺环已脲;Acetohexamid
储存和溶解度
DMSO:>10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
