1-OCTanol 是一种饱和脂肪醇,是一种 T 型钙通道抑制剂,对天然 T 电流的IC50为 4 μM。它是一种具有类似柴油特性的极具吸引力的生物燃料。
产品描述
1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents[1]. 1-Octanol is a highly attractive biofuel with diesel-like properties[2].
体外活性
1-octanol inhibits native T-currents at subanesthetic concentrations with an IC50 of approximately 4 μM. In contrast, 1-octanol is up to 30-fold less potent in inhibiting recombinant CaV3.3 T-channels heterologously expressed in human embryonic kidney cells[1].
Cas No.
111-87-5
分子式
C8H18O
分子量
130.23
别名
正辛醇;Octanol
储存和溶解度
DMSO:250 mg/mL (1919.68 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years