RPR132595A(NPC)是CPT-11的活性代谢产物，它是由细胞色素P-4503A4(CYP3A4)产生并最终通过尿排出。
| Cas No. | 185304-42-1 |
| 别名 | NPC |
| Canonical SMILES | O=C(N1CCC(N)CC1)OC2=CC=C3N=C4C(CN5C(C(COC([C@@]6(CC)O)=O)=C6C=C54)=O)=C(CC)C3=C2 |
| 分子式 | C28H30N4O6 |
| 分子量 | 518.56 |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | RPR132595A (NPC) is an active metabolite of CPT-11, which is generated by cytochrome P-450 3A4 (CYP3A4) and finally excreted through urine[1]. [1]. Alvau MD, et al. Enzyme-Based Electrochemical Biosensor for Therapeutic Drug Monitoring of Anticancer Drug Irinotecan.Anal Chem. 2018 May 15;90(10):6012-6019. |
