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DBCO-acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
DBCO-acid图片
CAS NO:1353016-70-2

DBCO-acid 是一种可降解 (cleavable) ADC linker,可用于合成 ADC linker DBCO-NHS ester ,及偶联物 DBCO-PEG-MMAE 。
Cas No.1353016-70-2
别名11,12-二氢-Γ-氧代-二苯并[[F]偶氮-5-(6H)-丁酸
Canonical SMILESO=C(CCC(O)=O)N(C1)C2=C(C=CC=C2)C#CC3=C1C=CC=C3
分子式C19H15NO3
分子量305.33
溶解度DMSO: 100 mg/mL (327.51 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester , and drug-linker conjugates DBCO-PEG-MMAE [1].

[1]. Zimmerman ES, et al. Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system. Bioconjug Chem. 2014 Feb 19;25(2):351-61.

 
 
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