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DBCO-NHS ester
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
DBCO-NHS ester图片
CAS NO:1353016-71-3

DBCO-NHS ester 是一种可降解 (cleavable) 的 ADC 连接桥,用于抗体药物结合物 (ADCs) 的合成。
Cas No.1353016-71-3
别名二苯并环辛炔-N-羟基琥珀酰亚氨基基酯
Canonical SMILESO=C(N1CC2=CC=CC=C2C#CC3=CC=CC=C31)CCC(ON4C(CCC4=O)=O)=O
分子式C23H18N2O5
分子量402.4
溶解度DMSO: 100 mg/mL (248.51 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

DBCO-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[1]. Method for identifying potential drug target protein useful for development of antibody drug, and method for producing antibody directed against target protein. WO2018151301A1.

 
 
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