THP-PEG4-Pyrrolidine(N-Boc)-CH2OH 是基于 PEG 结构的 PROTAC linker, 可以用来制备 PROTAC K-Ras Degrader-1 。
Cas No. | 2378261-80-2 |
Canonical SMILES | O=C(N1[C@H](CO)C[C@@H](OCCOCCOCCOCCOC2CCCCO2)C1)OC(C)(C)C |
分子式 | C23H43NO9 |
分子量 | 477.59 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | THP-PEG4-Pyrrolidine(N-Boc)-CH2OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 [1]. [1]. CREW, Andrew P., et al. MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. WO2019195609A2. |