| CAS NO: | 1426164-52-4 |
| 包装 | 价格(元) |
| 100mg | 询价 |
| 250mg | 询价 |
| Cas No. | 1426164-52-4 |
| 别名 | 马来酰亚胺-酰胺-PEG2-酸 |
| Canonical SMILES | O=C(O)CCOCCOCCOCCOCCNC([C@@H](NC(CCN1C(C=CC1=O)=O)=O)CCCCNC(CCN2C(C=CC2=O)=O)=O)=O |
| 分子式 | C31H45N5O13 |
| 分子量 | 695.71 |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Bis-Mal-Lysine-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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