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DMG-PEG 2000
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
DMG-PEG 2000图片
CAS NO:160743-62-4
包装:500mg
市场价:4950元

DMG-PEG 2000 用于 siRNA 转染 (siRNA delivery) 的脂质体的制备,能够提高转染效率。DMG-PEG 2000 也可被用于脂质纳米颗粒制备,用于口服质粒 DNA 的体内传递途径,DMG-PEG 2000 可以提高纳米颗粒的黏液渗透性和传递效率。
Cas No.160743-62-4
Canonical SMILESCCCCCCCCCCCCCC(OC(COCCOC)COC(CCCCCCCCCCCCC)=O)=O.[n]
分子式(C2H4O)nC32H62O5
溶解度DMSO: 100 mg/mL
储存条件-20℃, sealed storage, away from moisture and light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles[1].

[1]. Tianqi Nie, et al. Surface Coating Approach to Overcome Mucosal Entrapment of DNA Nanoparticles for Oral Gene Delivery of Glucagon-like Peptide 1.ACS Appl Mater Interfaces. 2019 Aug 21;11(33):29593-29603.

 
 
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