O-glycosylation-IN-1 是一种有效的 O-糖基化抑制剂，用于减少细胞表面的粘蛋白。 O-糖基化-IN-1 抑制人胰腺癌细胞模型粘蛋白 O-糖基化的合成。
| Cas No. | 3554-93-6 |
| 别名 | 苄基-2-乙酰胺基-2-脱氧-Α-D-吡喃半乳糖苷 |
| Canonical SMILES | O[C@@H]([C@H]([C@@H](CO)O1)O)[C@@H](NC(C)=O)[C@H]1OCC2=CC=CC=C2 |
| 分子式 | C15H21NO6 |
| 分子量 | 311.33 |
| 溶解度 | Water: 8.33 mg/mL (26.76 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | O-glycosylation-IN-1 is a potent O-glycosylation inhibitor and is used to reduce mucin on cell surfaces. O-glycosylation-IN-1 inhibits the synthesis of mucin O-glycosylation of cellular models of human pancreatic cancer[1]. [1]. Kalra AV, et al. Mucin impedes cytotoxic effect of 5-FU against growth of human pancreatic cancer cells: overcoming cellular barriers for therapeutic gain. Br J Cancer. 2007 Oct 8;97(7):910-8. Epub 2007 Oct 2. |
