pCPA methyl ester hydrochloride 是色氨酸羟化酶抑制剂和5-HT合成的抑制剂。 pCPA methyl ester hydrochloride 可穿过血脑屏障并降低 5-HT 中枢可用性。

pCPA methyl ester hydrochloride is an inhibitor of tryptophan hydroxylase inhibitor and 5-HT synthesis. pCPA methyl ester hydrochloride is permeable across the blood-brain barrier and reduces 5-HT central availability.

In C57BL/6 elite male mice, 5-HT levels decreased by 85% and 55% in the hippocampus of mice treated with oral or i.p. PCPA methyl ester hydrochloride(250, 500 mg/kg), respectively, whereas in the prefrontal cortex, 5-HT levels decreased by 65% and 50%[4].

14173-40-1

C10H13Cl2NO2

250.12

4-Chloro-DL-phenylalanine methyl ester hydrochloride;4-氯-DL-苯基丙氨酸甲酯盐酸盐

DMSO:245 mg/mL (979.53 mM),Need ultrasonic
H2O:45 mg/mL (179.91 mM),ultrasonic and warming and heat to 60°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years