LX-1031 是一种有效的色氨酸 5-羟化酶抑制剂。 LX-1031 减少外周5-羟色胺的合成。
产品描述
LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally.
体内活性
LX-1031 reduces the expression of 5-HT in the duodenum, jejunum, and ileum in a dose-dependent manner, but has no effect on brain 5-HT levels in preclinical assay[1]. The average 5-HT reductions in the jejunum relative to control are appr 33, 51, and 66%
Cas No.
945976-76-1
分子式
C28H25F3N4O4
分子量
538.52
储存和溶解度
DMSO:30mg/mL (55.71 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
