NH2-PEG7是一种PROTAClinker(PROTAClinker)，属于PEG类。NH2-PEG7可用于PROTACPARP1降解剂iRucaparib-AP6的合成。
| Cas No. | 1425973-14-3 |
| 别名 | 氨基-七聚乙二醇 |
| Canonical SMILES | OCCOCCOCCOCCOCCOCCOCCN |
| 分子式 | C14H31NO7 |
| 分子量 | 325.4 |
| 溶解度 | DMSO: 100 mg/mL (307.31 mM); Water:< 0.1 mg/mL (insoluble) |
| 储存条件 | 4°C, away from moisture and light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | NH2-PEG7 is a PROTAC linker, which refers to the PEG composition. NH2-PEG7 can be used in the synthesis of the PROTAC PARP1 degrader iRucaparib-AP6[1]. [1]. Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation. Nat Chem Biol. 2019 Dec;15(12):1223-1231. |
